According to neuroscientists from the University of South Florida, marijuana could be considered as a possible treatment for Alzheimer's disease. Based on the results of their research, a compound in marijuana called Delta-9-tetrahydrocannabinol, or THC, has shown promising potential for slowing down the progress of this degenerative disease.
The scientist to say that their findings have revealed how THC in marijuana is able to suppress the production and accumulation of the soluble protein, amyloid beta, that has been found in increased levels in aging brains. The buildup of this substance in the brain is believed to be an early pathological marker of neurodegenerative diseases. Additionally, researchers have discovered that even long levels of THC can improve the mitochondrial function of the brain cells, which can be directly associated to an improvement in its energy supply, transmission of signals, and overall brain health.
According to lead author, Dr. Chuanhai Cao, a neuroscientist at the Byrd Alzheimer's Institute also from that USF College Of Pharmacy, "THC is known to be a potent antioxidant with neuroprotective properties, but this is the first report that the compound directly affects Alzheimer's pathology by decreasing amyloid beta levels, inhibiting its aggregation, and enhancing mitochondrial function. Decreased levels of amyloid beta means less aggregation, which may protect against the progression of Alzheimer's disease. Since THC is a natural and relatively safe amyloid inhibitor, THC or it's analogs may help us develop an effective treatment in the future."
Researchers also noted that the doses that were administered during the study did not increase the risk of THC toxicity or memory impairment. And, while their study shows how this compound in my one could be a therapeutic value in the generative diseases such as Alzheimer's disease, they emphasized that they are not promoting the use of illicit drugs for the prevention of the disease.
