The U.S. Food and Drug Administration (FDA) warns that taking grapefruit while on certain medications may cause some harmful interactions in the body. Although eating the fruit is part of a balanced diet, the FDA reveals that over fifty over-the-counter and prescription drugs can have negative interactions with it.
Here are some information about grapefruit and medication, as provided by the FDA.
How it does or doesn't work
Depending on the active ingredient, grapefruit can reduce the effectiveness of a drug or worse, create potentially dangerous drug levels in the body. Grapefruit can interfere with transporters in the intestine that help absorb drugs. When this happens, less of the drug reaches the bloodstream and the patient receives no benefit.
Grapefruit can also interfere with enzymes that break down drugs in your digestive system. This can result in the body absorbing too much of the drug, which can potentially cause serious problems.
Help may be on the way
Scientists are currently working on breeding hybrid grapefruits that will be safe to mix with medications. In the near future you may be able to enjoy these tasty mounds without compromising your safety. But until the new fruit containers start to arrive, follow these tips:
- Ask your pharmacist or other health care professional if you can have fresh grapefruit or grapefruit juice while using your medication. If you can't, you may want to ask if you can have other juices with the medicine.
- Read the Medication Guide or patient information sheet that comes with your prescription medicine to see if it interacts with grapefruit juice. Some information may advise not to take the drug with grapefruit juice. If it's OK to have grapefruit juice, there will be no mention of it in the guide or information sheet.
- Read the Drug Facts label on your non-prescription medicine, which will let you know if you can have grapefruit or other fruit juices with it.
- If you can't have grapefruit juice with your medicine, check the label of bottles of fruit juice or drinks flavored with fruit juice to make sure they don't contain grapefruit juice.
- Seville oranges (often used to make orange marmalade) and tangelos (a cross between tangerines and grapefruit) affect the same enzyme as grapefruit juice, so avoid these fruits as well if your medicine interacts with grapefruit juice.
From FDA.gov
